image segmentation of carotid artery

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I am trying to find the plaque in the carotid artery, and i want to make something which detects the edges of the wall of the artey but not any of the methods for edge tracking has helped. can you help me out?
the image is an ultra sound image.abnormal2.jpg
this an image with plaque(represented by dotted lines)
sample.jpg
this is a healthy artery
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SAURAV ANAND
SAURAV ANAND 2019-8-21
I found a research paper on this which shows to implement Completely User-Independent Layer EXtraction (CULEX) algorithm. But don't have the code. can anyone haelp me out with the code?
SAURAV ANAND
SAURAV ANAND 2019-8-21
The exact algorithm consists of the following steps:
1) Low pass filtering of the image (gaussian filter of the 50th order, standard deviation equal to 10) in order to increase signal-to-noise ratio.
2) Determination of the adventitial wall from the intensity profile of the image considered column wise. Specifically, for each column of the image, we identify the pixels possibly belonging to the adventitia as those local maxima whose intensity is in the 90th percentile of the intensity distribution. An example of a typical intensity profile derived along a column of the image is reported in Fig. 2.
3) Individuation of the carotid lumen as the minimum point on the intensity profile whose mean intensity and variance of the neighborhood belong to the lowest classes. The minimum is searched descending the intensity profile from the maxima found during step 2). When the minimum is reached, the corresponding point is taken as marker of the carotid lumen and the starting maximum as marker of the adventitia.
4) Iteration of steps 2) and 3) for all columns.

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